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Hektoen, presenting the substance of his paper in the form of remarks on the above, said: The fact that human fragmentation and segmentation are of such common occurrence in all sorts of conditions; the fact that it did not seem to be possible to produce these lesions experimentally; and the further fact that no changes of a reactive character about the fragments and segments were ever observed, led to the very reasonable conclusion that myocardial disunion was of intravital occurrence, most likely of agonal development, probably due to irregular contractions of the heart.

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